Multimodal neuroimaging plays an important role in neuroscience research.Integrated noninvasive neuroimaging modalities, such as magnetoencephalography(MEG),electroencephalography (EEG) and functional near-infrared spectroscopy(fNIRS),allow neural activity and related physiological processes in the brain to be precisely and comprehensively depicted, providing an effective and advanced platform to study brain function.Noncryogenic optically pumped magnetometer (OPMMEG has high signal power due to its on-scalp sensor layout and en ables more flexible configurations than traditional commercial superconducting MEG.Here we integrate OPM MEG with EEG and fNIRS to develop a multimodal neuroimaging system that can simultaneously measure brain electrophysiology and hemodynamics. We conducted a series of experiments to demonstrate the feasibility and robustness of our MEG-EEG-fNIRS acquisition system.The complementary neural and physiological signals si multaneously collected by our multimodal imaging system provide opportunities for a wide range of potential applications in neurovascular coupling,wearable neuroimaging,hyperscanning and brain-computer interfaces.
